Month: December 2023

Dexamethasone is a synthetic glucocorticoid—that is, it is similar to a natural hormone produced by the adrenal glands—and is used primarily for its potent anti-inflammatory effect. As such, it is used to treat certain forms of arthritis; disorders of the skin, blood, kidneys, eyes, thyroid, and intestines (e.g., colitis); severe allergies; and asthma.The… Read More... "Obtaining Dexamethasone Acid from Dexamethasone"

By Nayeli Ramirez Most drug degradation mechanisms include hydrolysis/dehydration, oxidation, isomerization/epimerization, decarboxylation, rearrangement, dimerization/polymerization and photolysis reactions. Some reactions, also, involve interaction with some excipients. The formation of degradation products can take place under different conditions, including acidic, basic, oxidative and photolytic conditions. Hydrolysis reactions can beseen as a result of... Read More... "Maillard's reaction".