Prediction of possible degradation products under stable conditions and calculation of toxicological alerts.
This service provides answers to questions that arise during the formulation stage of a drug and its stability testing, such as:
- What compounds can be formed by excipient-active ingredient (API) interaction in a given formulation?
- Do these compounds have a high toxicological potential?
- Could they be a risk to the stability of my drug and could they pose a risk to the registration of a drug?
Through Toxscreen 's service, our customers know the possible chemical interactions between the API and the excipients, as well as the degradation products that can be formed in a given combination under standard stability conditions. We also evaluate the potential toxicological alerts of each compound and determine the risk of it being potentially present in a pharmaceutical product.
Therefore, it provides useful and very fast information for decision making in different areas of drug development and manufacturing:
- Preformulation and reformulation
- Stability
- Analytical development